Water deficit or drought has an adverse effect on crop production, and it is one of the limiting factors of world food security. A field experiment was conducted on different maize genotypes in University of Debrecen to assess the impact of water deficit on the physiology, grain nutrition and yield of three maize genotypes. The studied treatments were full irrigation and non-irrigation. The irrigated treatment did not significantly affect grain yield and starch content. Grain protein, moisture content SPAD and leaf area index(LAI) were significantly affected by irrigation. There was significant yield difference between the hybrids and grain nutrition quality was also affected by hybrids difference at LSD 1%. For good nutritional quality grain from the studied genotypes, the researchers propose (P 9911) Genotype under similar environmental condition.